Retrieved 14 November The SmartFlare is a minor part of the article. But keep in mind that the same gene regulation effect can be seen with multivalent oligonucleotide nanoparticles of varying cores, such as self-assembled micellar structures, e. Wrighton on microelectrode devices for electrocatalysis. In , he was listed as the most cited chemist in the world over the last decade in terms of total citations, the second highest most cited chemist  in terms of impact factor,  and the top most cited nanomedicine researcher. From Wikipedia, the free encyclopedia.
Patents related to therapeutically targeting Nodal in tumor cells have been awarded to E. Beckman Young Investigators, — Retrieved January 31, In other projects Wikimedia Commons. Mirkin has pioneered the use of DNA and nanoparticles as synthons in materials science and the development of nanoparticle -based biodiagnostics. Given that we are talking about experiments on humans, I would have thought that this is a pretty serious concern. This is the most basic, surprising, unexpected and critical feature of these materials.
If desorption occurs due to breaking of the Au-S bond, there cannot be specificity. Email Address never made public.
Archived from the original on 14 November Some readers might wonder why I am going on about this, so let me tell you: Therefore we would be in a position where dozens of papers on the basic technology underpinning the clinical trials are, at the very least, questionable. The report produced by the committee calls for sustaining the investments in advanced science and technology that produced America’s innovation economy and the establishment of a National Network of Manufacturing Innovation Institutes.
Views Read Edit View history. CoI statement from the paper: Inhe was listed as the most cited chemist in the world over the last decade in terms of total citations, the second highest most cited chemist  in terms of impact factor,  and the top most cited nanomedicine researcher. These discoveries and innovations have led to over commercial products that are being used worldwide.
Antisense gene regulation cannot happen without the particles going out of the endosomes.
The author is a journalist working for the magazine, not a practicing scientist. Retrieved 21 January This site uses Akismet to reduce spam.
You are commenting using your Google account. But keep in mind that the same gene regulation effect can be seen with multivalent oligonucleotide nanoparticles of varying cores, such as self-assembled micellar structures, e. Fill in your details below or click an icon to log in: In addition to his chae and research work, Mirkin has been involved in shaping science policy decisions.
Reference  correspond to six half a dozen articles, 80a to 80f see below for details and links. Let me refine those last sentences: Retrieved 14 November Mine is not an indiscriminate bashing but mirin careful candid critique, based on published papers including their massive holesbasic knowledge of cell biology, as well as our own results: Leave a Reply Cancel reply Enter your comment here Phoenix, ArizonaU.
I happen to agree with you that the flares lighting up in the endosome is a serious issue to be addressed and most certainly interferes with accurate detection of mRNA.
The authors are from Northwestern, i. In other projects Wikimedia Commons.
Chad Mirkin – Wikipedia
I agree; edited accordingly. Beckman Young Investigators, — Archived from the original on Retrieved 17 November His work with SNA-gold nanoparticle conjugates introduced the concept of a nanoparticle as an atom and nucleic acids as bonds, and it laid the ground work for the fields of colloidal crystal engineering with DNA and molecular diagnostics based upon well-defined nanoparticle and nanocrystal bioconjugates.
Chad Alexander Mirkin born November 23, is an American chemist. It does not show in any way that SmartFlares work. Post was not sent – check your email addresses!