THESIS ON INDUCIBLE CLINDAMYCIN RESISTANCE

Considering the number of submitted samples, the most frequent inducible resistant microorganisms were retrieved from internal medicine wards. Internet J Microbiol ; 9. All the erythromycin-sensitive strains were excluded. In regard to the number of samples, urine specimens revealed the most frequency. The macrolide, lincosamide and streptogramin B MLSB family including clindamycin as one of the best preferred agents serves as one of these alternatives 2.

The macrolide, lincosamide and streptogramin B MLSB family including clindamycin as one of the best preferred agents serves as one of these alternatives 2. Constitutive resistance can normally be detected by routine standard susceptibility testing whereas strains that demonstrate inducible resistance cannot be recognized by routine broth or agar based susceptibility tests 1 , 3 , 8. Routine quality control of the disks was performed by S. Abstract Background and Objectives: The increasing prevalence of methicillin resistance among Staphylococci is an increasing problem. Accurate designation of antimicrobial susceptibility pattern of the infecting microorganisms is an important crucial factor in making appropriate therapeutic decisions 2 ,

Data have are shown in Table 2. Constitutive resistance can normally be detected by routine standard susceptibility testing whereas strains that demonstrate inducible resistance cannot be recognized by routine broth or agar based susceptibility tests 138. Complementary quality control for D-test also was done with selected in-house strain that was D-test positive.

Prevalence of inducible clindamycin resistance in Gram positive organisms in a tertiary care center. J Med Microbiol ; In our study the rate of inducible and constitutive clindamycin resistance among erythromycin resistant microorganisms was Accurate susceptibility data are important for appropriate therapy decisions.

  ESSAY AFIRMASI LPDP

Detection of inducible clindamycin resistance among Staphylococcal isolates from different clinical specimens in western India. Detection of inducible clindamcin resistance of staphylococci in conjuction with performance of automated broth susceptibility testing.

Although they are structurally different, their mode of action is similar 14. If they were resistant to erythromycin and sensitive to clindamycin in primary antibiotic susceptibility testing by Kirby-Bauer method, they were subjected to D-zone testing to detect possible inducible clindamycin resistance.

Clindamycin has good oral bio-availability and is helpful for outpatient therapy or as oral agent can be followed after intravenous therapy 2. Both of these studies approximately supported our findings.

thesis on inducible clindamycin resistance

Indian J pathol Microbiol ; inducjble The prevalence of inducible clindamycin resistance among gram positive cocci from various clinical specimens. Amongst MLSB group, clindamycin has been considered as the preferred agent due to its excellent pharmacokinetic properties 1245 including good penetration and distribution in to the skin and other soft tissue structures 6 and acceptable oral absorption with no dosage adjustment in renal disorders 1. Determination of antimicroial susceptibility patterns and inducible clindamycin resistance in Staphylococcus aureus strains recovered from southeastern Turkey.

Inducible Clindamycin Resistance in Staphylococcus aureus Isolated from Clinical Samples

Antimicrob Agents Chemother ; Comparison of four diagnostic methods for detection kn methicillin resistant Staphylococcus aureus. Inducible clindamycin resistancein Staphylococci: This article has been cited by other articles in PMC.

thesis on inducible clindamycin resistance

Also, we aimed to evaluate any possible correlation between the frequency of inducible clindamycin resistance and susceptibility pattern to methicillin in staphylococci. J Microbiol Immunol Infect ; Detection of inducible clindamycin resistance in Staphylococus aureus and coagulase-negative staphylococci- a study from South India.

  QUANTUM MECHANICS HOMEWORK SOLUTIONS LIBOFF

Amongst MLSB group, clindamycin has been considered as the preferred agent due to its excellent pharmacokinetic properties 1245 including good penetration and distribution in to the skin and other soft tissue structures 6 and acceptable oral ressistance with no dosage adjustment in renal disorders 1.

J Clin Microbiol ; Result of D-test analysis was shown in Table 1.

Jundishapur Journal of Microbiology

Thirty three out of isolates of Staphylococcus aureus and 50 out of isolates of coagulase-negative staphylococci CoNS were subjected for D-zone testing. Frequency of susceptibility patterns towards erythromycin and clindamycin clinamycin streptococci.

Antimicrob Agents Chemother ; Open in a separate window. In our study we found high percentage of erythromycin-resistant S. Positive D-test was observed in Routine quality control of the disks was performed by S.

On the other hand negative result for inducible clindamycin resistance confirms clindamycin susceptibility and provides a very good therapeutic option. Detection of inducible clindamycin resistance in Staphylococus aureus and coagulase-negative staphylococci- a study from South India.